Cefoperazone Sulbactam 1.5g Injections

Product

Adult dose

Pediatric dose

Adjustment in Renal / Hepatic Impaired patients

Kephazon-S Forte

In normal infection 1.5-3g

In severe or refractory infections-12g every 12 hours in equality divided doses.

Normal infection 30-60 mg/kg/day

In serious or refractory infections 240 mg/kg day in 2 or 4 equally divided doses.

Yes

Product name

Composition

Indication/s

Strengths

Packing

Kephazon-S Forte

Cefaperazone + Sulbactam (2:1)

IAI,PID, UTI, VAP, Sepsis, Febrile neutropenia, renally impaired ICU patients, Prophylaxis in Pre/Post Operative infections

1.5 g

1 Vial

3.0g

1 Vial

Product name

Storage

Stability after reconstitution

Prep of solution

Diluent

Kephazon-S- Forte  (Cefoperazone/Sulbactam (2:1) 1.5g/3gVials)

Store below 25ºC

Protect from light

24 hr if controlled at 15ºC to 25ºC, 5 days if controlled at 2ºC to 8ºC, 3 weeks if controlled at -20º to -10ºC

For intravenous infusion, each vial of sulbactam/cefoperazone should be reconstituted with the appropriate amount of 5% dextrose, 0.9% sodium chloride injection or sterile water for injection as mentioned above and then further diluted to 20mL with the same solution followed by administration over 15-60 mins. Lactated Ringer's solution is a suitable vechile for intravenous infusion, however not for initial reconstitution. For intravenous inj. Each vial should be reconstituted as above and administered over a minimum of 3 mins.

5% Dextrose in water,

5% dextrose in 0.225% saline

5% dextrose in normal saline,

0.9% NaCI injection