Colistimethate Sodium for Injection IP

Product

Adult dose

Pediatric dose

Adjustment in Renal / Hepatic Impaired patients

Colicraft

Over 60 kg 1-2 million units TID, The maximum dose is 6 MU IN 24 HOURS.

Up to 60 kg: 50,000 units/kg/day, to a maximum of 75,000 units/kg/day TID

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Yes

Product name

Composition

Indication/s

Strengths

Packing

Colistimethate

Gram Negative injection

Particularly when the infection is caused by sensitive strains of P.aeruginosa, E.aerogenes, E.coil, K.pneumonia

2 million IU

1 Vial

Colistimethate sodium

Product name

Storage

Stability after reconstitution

Prep of solution

Diluent

Colicraft (Colistimethate sodium I Million IU vial)

Store at 25ºC-25ºC in a cool place.

Reconstituted solution is can be refrigerater at 2ºC-8ºC used with in 7 days

IC infusion: Each dose of CMS can be diluted with 10-50 ml and administered by IV infusion over a period of 30 minutes.

Normal saline 5% dextrose in water 5% dextrose in Normal saline 5% Dextrose wth 0.455 NaCl, 5% Dextrose with 0.225% NaCl